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Line-field confocal optical coherence tomography

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Abstract

A time-domain optical coherence tomography technique is presented for ultrahigh-resolution B-scan imaging in real-time. The technique is based on a two-beam interference microscope with line illumination and line detection, using a supercontinuum laser and a line-scan camera. Multiple (2048) A-scans are acquired in parallel by scanning the sample depth while adjusting the focus. A quasi isotropic spatial resolution of 1.3 µm × 1.1 µm (lateral × axial) is achieved. In vivo cellular level resolution imaging of normal and cancerous human skin is demonstrated at 10 frame/s with a penetration depth of ∼ 500 µm.
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Dates and versions

hal-02197158 , version 1 (30-07-2019)

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Jonas Ogien, Olivier Levecq, Hicham Azimani, Arthur Davis, Weikai Xue, et al.. Line-field confocal optical coherence tomography. SPIE's International Symposium on Biomedical Optics (BiOS), Feb 2019, San-Francisco, United States. ⟨10.1117/12.2507244⟩. ⟨hal-02197158⟩
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