Line-field confocal time-domain optical coherence tomography with dynamic focusing

Arnaud Dubois 1 Olivier Levecq 1 Hicham Azimani 1 Arthur Davis 1 Jonas Ogien 1 David Siret 1 Anaïs Barut
1 Laboratoire Charles Fabry / Biophotonique
LCF - Laboratoire Charles Fabry
Abstract : A time-domain optical coherence tomography technique is introduced for high-resolution B-scan imaging in real-time. The technique is based on a two-beam interference microscope with line illumination and line detection using a broadband spatially coherent light source and a line-scan camera. Multiple (2048) A-scans are acquired in parallel by scanning the sample depth while adjusting the focus. Quasi-isotropic spatial resolution of 1.3 µm × 1.1 µm (lateral × axial) is achieved. In vivo cellular-level resolution imaging of human skin is demonstrated at 10 frames per second with a penetration depth of ∼500 µm.
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Journal articles
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https://hal-iogs.archives-ouvertes.fr/hal-01950735
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Submitted on : Tuesday, December 11, 2018 - 8:56:47 AM
Last modification on : Friday, December 21, 2018 - 1:13:01 AM
Long-term archiving on : Tuesday, March 12, 2019 - 1:17:13 PM

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IOGS | LCF_BIOPHOTONIQUE | LCFIO | PARISTECH | UNIV-PARIS-SACLAY

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Arnaud Dubois, Olivier Levecq, Hicham Azimani, Arthur Davis, Jonas Ogien, et al.. Line-field confocal time-domain optical coherence tomography with dynamic focusing. Optics Express, Optical Society of America, 2018, 26 (26), pp.33534. ⟨10.1364/oe.26.033534⟩. ⟨hal-01950735⟩

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