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Skin lesion imaging with line-field confocal optical coherence tomography

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Maxime Cazalas
  • Function : Author
Anaïs Barut
  • Function : Author
Mariano Suppa
Véronique del Marmol
  • Function : Author
Josep Malvehy
Pietro Rubegni
  • Function : Author
Jean-Luc Perrot
  • Function : Author
Arnaud Dubois

Abstract

An original OCT technique called line-field confocal OCT (LC-OCT) is presented. Combining the principles of time-domain OCT and confocal microscopy with line illumination and detection, LC-OCT acquires multiple A-scans in parallel with dynamic focusing. With a quasi isotropic resolution of 1 µm, the LC-OCT images reveal a comprehensive structural mapping of skin, in vivo, at the cellular level down to a depth of 500 µm. LC-OCT images of various skin lesions, including carcinomas and melanomas, are found to strongly correlate with histopathological images. LC-OCT could significantly improve clinical diagnostic accuracy, while reducing the number of biopsies of benign lesions.
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BiOS 2019 - LC-OCT in dermatology (oral) - 250 words.pdf (217.7 Ko) Télécharger le fichier
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Dates and versions

hal-02197166 , version 1 (30-07-2019)

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Maxime Cazalas, Olivier Levecq, Hicham Azimani, David Siret, Anaïs Barut, et al.. Skin lesion imaging with line-field confocal optical coherence tomography. SPIE's International Symposium on Biomedical Optics (BiOS), Feb 2019, San-Francisco, United States. ⟨10.1117/12.2508484⟩. ⟨hal-02197166⟩
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