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Skin lesion imaging with line-field confocal optical coherence tomography

Abstract : An original OCT technique called line-field confocal OCT (LC-OCT) is presented. Combining the principles of time-domain OCT and confocal microscopy with line illumination and detection, LC-OCT acquires multiple A-scans in parallel with dynamic focusing. With a quasi isotropic resolution of 1 µm, the LC-OCT images reveal a comprehensive structural mapping of skin, in vivo, at the cellular level down to a depth of 500 µm. LC-OCT images of various skin lesions, including carcinomas and melanomas, are found to strongly correlate with histopathological images. LC-OCT could significantly improve clinical diagnostic accuracy, while reducing the number of biopsies of benign lesions.
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https://hal-iogs.archives-ouvertes.fr/hal-02197166
Contributor : Arnaud Dubois <>
Submitted on : Tuesday, July 30, 2019 - 2:08:25 PM
Last modification on : Thursday, November 21, 2019 - 2:02:42 AM

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Maxime Cazalas, Olivier Levecq, Hicham Azimani, David Siret, Anaïs Barut, et al.. Skin lesion imaging with line-field confocal optical coherence tomography. SPIE's International Symposium on Biomedical Optics (BiOS), Feb 2019, San-Francisco, United States. ⟨10.1117/12.2508484⟩. ⟨hal-02197166⟩

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