Mutating the cholesterol binding site on amyloid precursor protein alters the processing and production of Aβ-amyloid peptides

Linda Hanbouch (1) , Marquer C. (1) , L. Boussicault (1) , Béatrice Schaack (2) , Karen Perronet (3) , Julien Moreau (3) , Nicolas Gilles (4) , Louis C. (5) , Millian M.J. (5) , Marie Claude Potier (1)

1 ICM - Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute
2 IBS - UMR 5075 - Institut de biologie structurale
3 Laboratoire Charles Fabry / Biophotonique
4 Centre de recherche du CEA/DSV/iBiTec-S/SIMOPRO
5 IRIS - Institut de Recherches Internationales Servier [Suresnes]

Domaines: Biophysique

Linda Hanbouch, Marquer C., L. Boussicault, Béatrice Schaack, Karen Perronet, et al.. Mutating the cholesterol binding site on amyloid precursor protein alters the processing and production of Aβ-amyloid peptides. ECNP Workshop for Junior Scientists in Europe, Mar 2018, Nice, France. ⟨hal-01809016⟩