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Advances in optical coherence tomography for dermatology (Orale)

Abstract : This paper reports on advances in optical coherence tomography (OCT) for application in dermatology. Full-field OCT is a particular approach of OCT based on white-light interference microscopy. FF-OCT produces en face tomographic images by arithmetic combination of interferometric images acquired with an area camera and by illuminating the whole field of view with low-coherence light. The major interest of FF-OCT lies in its high imaging spatial resolution (∼ 1.0 µm) in both lateral and axial directions, using a simple and robust experimental arrangement. Line-field OCT (LF-OCT) is a recent evolution of FF-OCT with line illumination and line detection using a broadband spatially coherent light source and a line-scan camera in an interference microscope. LF-OCT and FF-OCT are similar in terms of spatial resolution. LF-OCT has a significant advantage over FF-OCT in terms of imaging penetration depth due to the confocal gate achieved by line illumination and detection. B-scan imaging using FF-OCT requires the acquisition of a stack of en face images, which usually prevents in vivo applications. B-scan imaging using LF-OCT can be considerably faster due to the possibility of using a spatially coherent light source with much higher brightness along with a high-speed line camera. Applied in the field of dermatology, the LF-OCT images reveal a comprehensive morphological mapping of skin tissues in vivo at a cellular level similar to histological images.
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Submitted on : Wednesday, April 4, 2018 - 9:38:43 AM
Last modification on : Wednesday, September 16, 2020 - 5:48:14 PM

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  • HAL Id : hal-01757843, version 1
  • ARXIV : 1804.01688

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Olivier Levecq, Arthur Davis, Hicham Azimani, David Siret, Jean-Luc Perrot, et al.. Advances in optical coherence tomography for dermatology (Orale). SPIE Photonics Europe, Apr 2018, Strasbourg, France. ⟨hal-01757843⟩

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