Spatial resolution versus contrast trade-off enhancement in high-resolution surface plasmon resonance imaging (SPRI) by metal surface nanostructure design

Abstract : Surface plasmon resonance imaging (SPRI) is an optical near-field method used for mapping the spatial distribution of chemical/physical perturbations above a metal surface without exogenous labeling. Currently, the majority of SPRI systems are used in microarray biosensing, requiring only modest spatial resolution. There is increasing interest in applying SPRI for label-free near-field imaging of biological cells to study cell/surface interactions. However, the required resolution (sub-μm) greatly exceeds what current systems can deliver. Indeed, the attenuation length of surface plasmon polaritons (SPP) severely limits resolution along one axis, typically to tens of μm. Strategies to date for improving spatial resolution result in a commensurate deterioration in other imaging parameters. Unlike the smooth metal surfaces used in SPRI that support purely propagating surface modes, nanostructured metal surfaces support “hybrid” SPP modes that share attributes from both propagating and localized modes. We show that these hybrid modes are especially well-suited to highresolution imaging and demonstrate how the nanostructure geometry can be designed to achieve sub-μm resolution while mitigating the imaging parameter trade-off according to an application-specific optimum.
Type de document :
Article dans une revue
Optics Express, Optical Society of America, 2018, 26 (8), pp.10616
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Contributeur : Marie-Laure Edwards <>
Soumis le : mardi 3 avril 2018 - 16:49:00
Dernière modification le : mercredi 12 décembre 2018 - 15:33:35

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  • HAL Id : hal-01757515, version 1

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F. Banville, Julien Moreau, Mitradeep Sarkar, Mondher Besbes, Michael Canva, et al.. Spatial resolution versus contrast trade-off enhancement in high-resolution surface plasmon resonance imaging (SPRI) by metal surface nanostructure design. Optics Express, Optical Society of America, 2018, 26 (8), pp.10616. 〈hal-01757515〉

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