Compact 5-LEDs illumination system for multi-spectral surface plasmon resonance sensing

Abstract : In this contribution, we quantify the performances of a low-cost, compact, multi-spectral illumination system allowing spectral interrogation to be performed in surface plasmon resonance imaging (SPRI) systems. Previous work demonstrated the feasibility of spectral interrogation based on a discrete number of scanning wavelengths using a white source and monochromator. Here, we expand this concept by building a multi-spectral SPRI system with five light-emitting diodes (LEDs). The development focuses on the improvement of the illumination stability, which is a critical parameter for the precision of the spectral interrogation measurement. The obtained prototype exhibits sensitivity and resolution properties comparable with reflectivity-interrogation-based SPRI systems, with the advantages of spectral interrogation, i.e. increased dynamical range and robustness towards solution index variations. These performances, as well as the real-time and 2-dimensional imaging modalities of the five-LEDs setup, are illustrated by a standard experiment of DNA–DNA interaction monitoring on a biochip format.
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Sensors and Actuators B: Chemical, Elsevier, 2015, 209, pp.208-211. 〈10.1016/j.snb.2014.11.080〉
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Contributeur : Julien Moreau <>
Soumis le : vendredi 27 novembre 2015 - 14:53:03
Dernière modification le : mercredi 17 janvier 2018 - 13:34:02

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Alexandra Sereda, Julien Moreau, Marine Boulade, Aurore Olivéro, Michael Canva, et al.. Compact 5-LEDs illumination system for multi-spectral surface plasmon resonance sensing. Sensors and Actuators B: Chemical, Elsevier, 2015, 209, pp.208-211. 〈10.1016/j.snb.2014.11.080〉. 〈hal-01230282〉

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