Nanofluidics in cellular tubes under oscillatory extension

Pierre Nassoy 1 Damien Cuvelier 1 Robijn Bruinsma 2 Françoise Brochard-Wyart 1, *
* Auteur correspondant
1 PCC - Physico-Chimie-Curie
2 Department of Physics and Astronomy [UCLA, Los Angeles]
Abstract : Membrane nanotubes or tethers extruded from cells exhibit dynamic features that are believed to exhibit viscoelastic rheological properties. We have performed typical microrheology experiments on tethers pulled from red blood cells by measuring the force response to small oscillatory extensions or compressions. Our data, supported by a simple theoretical model, show that the force response does not reflect any intrinsic viscoelastic properties of the tethers themselves, but instead is dominated by the drainage of the internal cellular fluid into and out of the oscillating nanoconduit over a frequency-dependent penetration depth. The simplicity of tether rheology suggests its usage as a probe for measuring the local viscosity of the cytosol near the plasma membrane.
Keywords : ERYTHROCYTE-MEMBRANE P-SELECTIN TETHER CELLS CYTOSKELETON TRANSPORT ADHESION DYNAMICS VESICLES FLOW
Type de document :
Article dans une revue
EPL - Europhysics Letters, European Physical Society/EDP Sciences/Società Italiana di Fisica/IOP Publishing, 2008, 84 (1), pp.18004. 〈10.1209/0295-5075/84/18004〉
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Contributeur : Pierre Nassoy <>
Soumis le : jeudi 9 mai 2013 - 12:27:25
Dernière modification le : vendredi 31 août 2018 - 09:18:24

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Pierre Nassoy, Damien Cuvelier, Robijn Bruinsma, Françoise Brochard-Wyart. Nanofluidics in cellular tubes under oscillatory extension. EPL - Europhysics Letters, European Physical Society/EDP Sciences/Società Italiana di Fisica/IOP Publishing, 2008, 84 (1), pp.18004. 〈10.1209/0295-5075/84/18004〉. 〈hal-00821357〉

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