Toxicology and Biodegradability of a Phthalate-Free and Bio-Based Novel Plasticizer
Résumé
Phthalate esters, mainly di-ethylhexylphthalate (DEHP), represent a class of chemicals primarily used as plasticizers for polyvinyl chloride in a wide range of domestic and industrial applications. ese phthalate esters are low-toxicity environmental contaminants. To address these drawbacks, POLYSORB ® ID 37, a blend of diesters obtained from esterification of isosorbide with plant-based fatty acids, was developed. e company can now offer PVC manufacturers a new product which competes with phthalates and other such chemicals. e market for plasticizers is very important, and ROQUETTE intends to provide a more sustainable and safer product. Isosorbide diester is bio-based (made from glucose and vegetable fatty acids). is plasticizer is registered in REACH regulation for high volumes (>1000 T/year). Risk assessment was obtained by conducting a wide range of biodegradability and toxicological protocols, using rodent models, according to established guidelines. Overall, all of the toxicological and biodegradability studies demonstrated that POLYSORB ® ID 37 is nontoxic to mammalian life and is readily biodegradable.
Domaines
Toxicologie
Origine : Publication financée par une institution