Toward the suppression of cellular toxicity from single-walled carbon nanotubes

Zhenghong Gao (1) , Juan A. Varela (2) , Laurent Groc (2) , Brahim Lounis (1) , Laurent Cognet (1, 3)

1 LP2N - Laboratoire Photonique, Numérique et Nanosciences
2 IINS - Interdisciplinary Institute for Neuroscience [Bordeaux]
3 lp2n-04,lp2n-12

In the multidisciplinary fields of nanobiology and nanomedicine, single-walled carbon nanotubes (SWCNTs) have shown great promise due to their unique morphological, physical and chemical properties. However, understanding and suppressing their cellular toxicity is a mandatory step before promoting their biomedical applications. In light of the flourishing recent literature, we provide here an extensive review on SWCNT cellular toxicity and an attempt to identify the key parameters to be considered in order to obtain SWCNT samples with minimal or no cellular toxicity.

Domaines: Toxicologie

Zhenghong Gao, Juan A. Varela, Laurent Groc, Brahim Lounis, Laurent Cognet. Toward the suppression of cellular toxicity from single-walled carbon nanotubes. Biomaterials Science, 2016, 4 (2), pp.230-244. ⟨10.1039/c5bm00134j⟩. ⟨hal-01390062⟩