Rotavirus P[8] Infections in Persons with Secretor and Nonsecretor Phenotypes, Tunisia

Siwar Ayouni (1, 2) , Khira Sdiri-Loulizi , Alexis de Rougemont (3, 4, 1, 5) , Marie Estienney (1) , Katia Ambert-Balay (1) , Serge Aho (6) , Sabeur Hamami , Mahjoub Aouni (2) , Mohamed Neji-Guediche , Pierre Pothier (7) , Gaël Belliot (4)

1 Laboratoire de sérologie-virologie (CHU de Dijon)
2 FPHM - Faculté de Pharmacie [Monastir]
3 UFR des Sciences de Santé (Université de Bourgogne)
4 CNR virus entériques - Centre National de Référence des virus entériques [CHU de Dijon]
5 PAM - Procédés Alimentaires et Microbiologiques [Dijon]
6 CEP - Centre d'épidémiologie des populations
7 LIMA - Laboratoire Interactions Muqueuses Agents Transmissibles

To determine whether rotavirus infections are linked to se-cretor status, we studied samples from children in Tunisia with gastroenteritis. We phenotyped saliva for human blood group antigens and tested feces for rotavirus. Rotavirus was detected in 32/114 patients. Secretor genotyping showed that P[8] rotavirus infected secretors and nonsecretors, and infection correlated with presence of Lewis antigen.

Domaines: Virologie; Maladies infectieuses

Siwar Ayouni, Khira Sdiri-Loulizi, Alexis de Rougemont, Marie Estienney, Katia Ambert-Balay, et al.. Rotavirus P[8] Infections in Persons with Secretor and Nonsecretor Phenotypes, Tunisia. Emerging Infectious Diseases, 2015, 21 (11), pp.2055-2058. ⟨10.3201/eid2111.141901⟩. ⟨hal-02290985⟩