Epidemiology of rotavirus infection among young children with acute diarrhoea in Burkina Faso.

Isidore J O Bonkoungou (1) , Idrissa Sanou (2) , Fabienne F. Bon (3) , Benoit Benon (4) , Sheick O Coulibaly (5) , Kaisa Haukka (6) , Alfred S Traoré (7) , Nicolas Barro (7)

1 CRSBAN/UFR SVT - Laboratoire de Biochimie et de Biologie Moléculaire
2 Laboratoire de Bactériologie et Virologie du CHU-Yalgado Ouédraogo
3 LIMA - Laboratoire Interactions Muqueuses Agents Transmissibles
4 Service de pédiatrie, Centre Médical du Secteur 30 de Ouagadougou
5 Laboratoire National de Santé Publique, OUagadougou
6 Department of Infectious Disease Surveillance and Control
7 CRSBAN/UFR-SVT - Laboratoire de Biochimie et Biologie Moléculaire

BACKGROUND: In anticipation of vaccine introduction, we assessed epidemiology of rotavirus disease among children visiting medical centre due to acute diarrhoea in Ouagadougou, Burkina Faso. METHODS: Between November 2008 and February 2010, stool specimens from 447 children less than 5 years of age suffering from diarrhoea were tested for the presence of rotavirus by antigen detection using an immunochromatographic test. Sociodemographic, environmental and clinical factors were assessed during the study. RESULTS: Rotavirus antigen was detected in 151 (33.8%) of the patients. Most of the cases (94.2%) were in children < 24 months of age. Fever and vomiting were the symptoms most commonly reported in association with rotavirus diarrhoea and the patients were often hospitalized. Rotavirus-associated diarrhoea occurred mostly during the season from December to April (dry season). Rotavirus infection was significantly less frequent in breast-fed than among bottle-fed babies. CONCLUSIONS: The results of this study underscore the need to control rotavirus infections among young children in Burkina Faso and may argue a decision on the introduction of rotavirus vaccine in Burkina Faso.

Mots clés: rotavirus; epidemiology

Domaines: Microbiologie et Parasitologie

Isidore J O Bonkoungou, Idrissa Sanou, Fabienne F. Bon, Benoit Benon, Sheick O Coulibaly, et al.. Epidemiology of rotavirus infection among young children with acute diarrhoea in Burkina Faso.. BMC Pediatrics, 2010, 10, pp.94. ⟨10.1186/1471-2431-10-94⟩. ⟨hal-00600916⟩