Corpus Callosum deformation analysis in Multiple Sclerosis

Foued Derraz (1) , Antonio Pinti (2) , Bruno Lenne (1) , Laurent Peyrodie (3) , Azzeddine Chikh (4) , Abdelmalik Taleb-Ahmed (2) , Patrick Hautecoeur (1)

1 GHICL - Groupe Hospitalier de l'Institut Catholique de Lille
2 LAMIH - Laboratoire d'Automatique, de Mécanique et d'Informatique industrielles et Humaines - UMR 8201
3 LAGIS-SI
4 GBM Lab - Laboratoire de recherches Génie Biomédicale

In this paper, we propose a new methodology for analyzing the deformations of the Corpus Callosum (CC) volume associated to Multiple Sclerosis (MS) lesion. We propose an approach for 3D segmentation of the volume of interest based on deformable models method. The measures are carried from the segmented brain volume obtained from MR and the deformation of the geometric shape is quantified. The deformations of the two ends as well as the thickness of the CC were retained to validate the method. The results allow evaluating the rate of deformation of the CC among patients from MRI sequences of patients with different level from handicap using the criterion established in this paper.

Mots clés: Image processing

Domaines: Traitement du signal et de l'image [eess.SP]; Traitement du signal et de l'image [eess.SP]

Foued Derraz, Antonio Pinti, Bruno Lenne, Laurent Peyrodie, Azzeddine Chikh, et al.. Corpus Callosum deformation analysis in Multiple Sclerosis. AMSE, 2010, 71 (3-4), pp.1-15. ⟨hal-00838381⟩