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Pulmonary arterial hypertension Humans Calcium Macrophages Inflammation Cytokines Inorganic arsenic Exposition professionnelle Farmer Bactérie Immunity Inflammatory diseases Arsenic Drug-drug interactions Environmental risk factors Ruxolitinib Silica Hypertension artérielle pulmonaire Air pollution Interleukin-8 Bretagne COPD Chronic obstructive pulmonary disease Bacteria Hepatoma Hepatocytes Toxicité Diesel exhaust Toxicokinetics Stress Eleveurs de bétail Cigarette smoke Drug transporter Dendritic cells Drug–drug interactions Crystalline silica Benzoapyrene Granulocyte-macrophage colony-stimulating factor Cytochrome P450 HepaRG cells Drug transporters Camp GM-CSF Human hepatocytes Polarization Oxidative stress Immunotoxicity Lait Nintedanib Whole lung lavage Apoptosis In vitro Epidemiology Bronchopneumopathie chronique obstructive Idiopathic pulmonary fibrosis Fibrose pulmonaire Macrophage Scleroderma Hepatocyte Cytochrome P-450 Heterocyclic amines Genotoxicity Docking Gene expression Comorbidity Chest tube drainage Toxicity Inhibition Pharmacokinetics Cancer Lung Pesticides Cell signaling NF-κB Immunité AhR Polycyclic aromatic hydrocarbons Systemic sclerosis Pneumopathie infiltrante diffuse Diesel exhaust particles Chest tube Aryl hydrocarbon receptor Dairy farmers Infection Risque professionnel Interstitial lung disease Differentiation Regulation Cardiovascular diseases Cardiovascular Bisphenol A Carcinogens Detoxification Cancer du pancréas France Dust exposure Nrf2 Polycyclic aromatic hydrocarbon Cytokine Efferocytosis