Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage

S Alsafadi (1) , A Houy (1) , A Battistella (1) , T Popova (1) , M. Wassef (2) , E Henry (3) , F Tirode (1) , A Constantinou (4) , S. Piperno-Neumann (5) , S Roman-Roman (3) , M Dutertre (6) , M. H. Stern (1)

1 U830 - Unité de génétique et biologie des cancers
2 Génétique et Biologie du Développement
3 Translational Research Department, Institut Curie, PSL Research University, Paris 75248, France
4 IGH - Institut de génétique humaine
5 Department of Medical Oncology, Institut Curie, Paris 75248, France
6 Stress génotoxiques et cancer

Domaines: Génétique

S Alsafadi, A Houy, A Battistella, T Popova, M. Wassef, et al.. Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage. Nature Communications, 2016, 7, pp.10615. ⟨10.1038/ncomms10615⟩. ⟨hal-01272099⟩